Reduction of Tumstatin in Asthmatic Airways Contributes to Angiogenesis, Inflammation, and Hyperresponsiveness

Publisher:
Amer Thoracic Soc
Publication Type:
Journal Article
Citation:
American Journal Of Respiratory And Critical Care Medicine, 2010, 181 (2), pp. 106 - 115
Issue Date:
2010-01
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Rationale Angiogenesis is a prominent feature of remodeling in asthma. Many proangiogenic factors are up-regulated in asthma, but little is known about levels of endogenous antiangiogenic agents. Collagen IV is decreased in the airway basement membrane i
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