Extraordinary conservation, gene loss, and positive selection in the evolution of an ancient neurotoxin

Society for Molecular Biology and Evolution
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Journal Article
Molecular Biology And Evolution, 2011, 28 (3), pp. 1173 - 1182
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The recent determination of the genetic basis for the biosynthesis of the neurotoxin, saxitoxin, produced by cyanobacteria, has revealed a highly complex sequence of reactions, involving over 30 biosynthetic steps encoded by up to 26 genes clustered at o
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