Topical Review: Metallic Nanoparticles Array For Immunoassay

Zhu, S; Fu, Y; Hou, J

Topical Review: Metallic Nanoparticles Array For Immunoassay

Zhu, S Fu, Y Hou, J

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Publisher:: Amer Scientific Publishers
Publication Type:: Journal Article
Citation:: Journal of Computational and Theoretical Nanoscience, 2010, 7 (10), pp. 1855 - 1869
Issue Date:: 2010-01

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Field	Value	Language
dc.contributor.author	Zhu, S	en_US
dc.contributor.author	Fu, Y	en_US
dc.contributor.author	Hou, J	en_US
dc.date.issued	2010-01	en_US
dc.identifier.citation	Journal of Computational and Theoretical Nanoscience, 2010, 7 (10), pp. 1855 - 1869	en_US
dc.identifier.issn	1546-1955	en_US
dc.identifier.uri	http://hdl.handle.net/10453/29307
dc.description.abstract	Noble metal particles, especially gold (Au) and silver (Ag) nanoparticles exhibit unique and tunable optical properties on account of their surface plasmon resonance (SPR).It can be widely used in the field of immunoassay.In this paper, we reviewed the design, fabrication methods and applications of the nanoparticles.Discrete dipole approximation (DDA) and finite difference time domain (FDTD) methods applied brute-force computational methods for calculation and analysis of optical properties of different nanoparticles.Current nanotechnologies such as focused ion beam (FIB), nanosphere lithography (NSL), and laser interference lithography (LIL) make it possible to fabricate nanoparticles with arbitrary shapes.These nanoparticles are used to detect binding signals excited from biosamples for immunoassay such as antibody and antigen, amyloidderived diffusible ligands (ADDLs)-potential Alzheimers disease (AD) biomarkers, and Staphylococcal enterotixn B (SEB) in the concentration of nano-Moore per liter (nM) level.Finally , a biochip with multi-channel detection of biotin-streptavidin based on localized surface plasmon resonance was introduced.	en_US
dc.publisher	Amer Scientific Publishers	en_US
dc.relation.ispartof	Journal of Computational and Theoretical Nanoscience	en_US
dc.relation.isbasedon	10.1166/jctn.2010.1551	en_US
dc.subject.classification	Nanoscience & Nanotechnology	en_US
dc.title	Topical Review: Metallic Nanoparticles Array For Immunoassay	en_US
dc.type	Journal Article
utslib.citation.volume	10	en_US
utslib.citation.volume	7	en_US
utslib.for	1007 Nanotechnology	en_US
utslib.for	0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics	en_US
utslib.for	0913 Mechanical Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
utslib.copyright.status	closed_access
pubs.consider-herdc	false	en_US
pubs.issue	10	en_US
pubs.volume	7	en_US

Abstract:

Noble metal particles, especially gold (Au) and silver (Ag) nanoparticles exhibit unique and tunable optical properties on account of their surface plasmon resonance (SPR).It can be widely used in the field of immunoassay.In this paper, we reviewed the design, fabrication methods and applications of the nanoparticles.Discrete dipole approximation (DDA) and finite difference time domain (FDTD) methods applied brute-force computational methods for calculation and analysis of optical properties of different nanoparticles.Current nanotechnologies such as focused ion beam (FIB), nanosphere lithography (NSL), and laser interference lithography (LIL) make it possible to fabricate nanoparticles with arbitrary shapes.These nanoparticles are used to detect binding signals excited from biosamples for immunoassay such as antibody and antigen, amyloidderived diffusible ligands (ADDLs)-potential Alzheimers disease (AD) biomarkers, and Staphylococcal enterotixn B (SEB) in the concentration of nano-Moore per liter (nM) level.Finally , a biochip with multi-channel detection of biotin-streptavidin based on localized surface plasmon resonance was introduced.

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http://hdl.handle.net/10453/29307