Long non-coding RNA-mediated mechanisms independent of the RNAi pathway in animals and plants

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Journal Article
RNA Biology, 2011, 8 (3), pp. 404 - 414
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Recent advances in the field of RNA research have provided compelling evidence implicating long non-coding RNA molecules in many diverse and substantial biological processes that include transcriptional and post-transcriptional regulation of gene expression, genomic imprinting, modulation of protein activity and subcellular localization and cellular structural maintenance. While long non-coding RNAs have been most extensively studied in animal species, studies of long non-coding RNA in plants begin to emerge showing some conservation of mechanisms. This review aims to provide an overview of significant and recently identified long non-coding RNA-mediated mechanisms in both animal and plant species. © 2011 Landes Bioscience.
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