Recent advances in molecular biology of parasitic viruses

Banik, GR; Stark, D; Rashid, H; Ellis, JT

Recent advances in molecular biology of parasitic viruses

Banik, GR Stark, D Rashid, H Ellis, JT

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Publication Type:: Journal Article
Citation:: Infectious Disorders - Drug Targets, 2014, 14 (3), pp. 155 - 167
Issue Date:: 2014-01-01

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Field	Value	Language
dc.contributor.author	Banik, GR	en_US
dc.contributor.author	Stark, D	en_US
dc.contributor.author	Rashid, H	en_US
dc.contributor.author	Ellis, JT https://orcid.org/0000-0001-7328-4831	en_US
dc.date.available	2014-07-15	en_US
dc.date.issued	2014-01-01	en_US
dc.identifier.citation	Infectious Disorders - Drug Targets, 2014, 14 (3), pp. 155 - 167	en_US
dc.identifier.issn	1871-5265	en_US
dc.identifier.uri	http://hdl.handle.net/10453/35761
dc.description.abstract	© 2014 Bentham Science Publishers B.V. All rights reserved. The numerous protozoa that can inhabit the human gastro-intestinal tract are known, yet little is understood of the viruses which infect these protozoa. The discovery, morphologic details, purification methods of virus-like particles, genome and proteome of the parasitic viruses, Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and the Eimeria sp. are described in this review. The protozoan viruses share many common features: most of them are RNA or double-stranded RNA viruses, ranging between 5 and 8 kilobases, and are spherical or icosahedral in shape with an average diameter of 30-40 nm. These viruses may influence the function and pathogenicity of the protozoa which they infect, and may be important to investigate from a clinical perspective. The viruses may be used as specific genetic transfection vectors for the parasites and may represent a research tool. This review provides an overview on recent advances in the field of protozoan viruses.	en_US
dc.relation.ispartof	Infectious Disorders - Drug Targets	en_US
dc.subject.classification	Microbiology	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Eimeria	en_US
dc.subject.mesh	Giardia lamblia	en_US
dc.subject.mesh	Trichomonas vaginalis	en_US
dc.subject.mesh	Entamoeba histolytica	en_US
dc.subject.mesh	RNA Viruses	en_US
dc.subject.mesh	RNA, Double-Stranded	en_US
dc.title	Recent advances in molecular biology of parasitic viruses	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.citation.volume	14	en_US
utslib.for	110803 Medical Parasitology	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	1101 Medical Biochemistry and Metabolomics	en_US
utslib.for	1115 Pharmacology and Pharmaceutical Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	closed_access
pubs.issue	3	en_US
pubs.publication-status	Published	en_US
pubs.volume	14	en_US

Abstract:

© 2014 Bentham Science Publishers B.V. All rights reserved. The numerous protozoa that can inhabit the human gastro-intestinal tract are known, yet little is understood of the viruses which infect these protozoa. The discovery, morphologic details, purification methods of virus-like particles, genome and proteome of the parasitic viruses, Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and the Eimeria sp. are described in this review. The protozoan viruses share many common features: most of them are RNA or double-stranded RNA viruses, ranging between 5 and 8 kilobases, and are spherical or icosahedral in shape with an average diameter of 30-40 nm. These viruses may influence the function and pathogenicity of the protozoa which they infect, and may be important to investigate from a clinical perspective. The viruses may be used as specific genetic transfection vectors for the parasites and may represent a research tool. This review provides an overview on recent advances in the field of protozoan viruses.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/35761