Induced adaptation of Bacillus sp. to antimicrobial nanosilver
- Publication Type:
- Journal Article
- Small, 2013, 9 (21), pp. 3554 - 3560
- Issue Date:
|SMALL_Gunawan et al_Nano Silver Antimicrobial Resistance 2013.pdf||Published Version||945.98 kB|
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The natural ability of Bacillus sp. to adapt to nanosilver cytotoxicity upon prolonged exposure is reported for the first time. The combined adaptive effects of nanosilver resistance and enhanced growth are induced under various intensities of nanosilver-stimulated cellular oxidative stress, ranging from only minimal cellular redox imbalance to the lethal levels of cellular ROS stimulation. An important implication of the present work is that such adaptive effects lead to the ultimate domination of nanosilver-resistant Bacillus sp. in the microbiota, to which nanosilver cytotoxicity is continuously applied. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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