Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

Ding, Y; Zhang, Y; Peng, T; Lu, Y; Jin, D; Ren, Q; Liu, Y; Han, J; Xi, P

Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

Ding, Y Zhang, Y Peng, T Lu, Y Jin, D

Ren, Q Liu, Y Han, J Xi, P

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Publication Type:: Journal Article
Citation:: Scientific Reports, 2013, 3
Issue Date:: 2013-06-11

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Field	Value	Language
dc.contributor.author	Ding, Y	en_US
dc.contributor.author	Zhang, Y	en_US
dc.contributor.author	Peng, T	en_US
dc.contributor.author	Lu, Y	en_US
dc.contributor.author	Jin, D https://orcid.org/0000-0003-1046-2666	en_US
dc.contributor.author	Ren, Q	en_US
dc.contributor.author	Liu, Y	en_US
dc.contributor.author	Han, J	en_US
dc.contributor.author	Xi, P	en_US
dc.date.available	2013-04-15	en_US
dc.date.issued	2013-06-11	en_US
dc.identifier.citation	Scientific Reports, 2013, 3	en_US
dc.identifier.uri	http://hdl.handle.net/10453/37059
dc.description.abstract	Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.	en_US
dc.relation.ispartof	Scientific Reports	en_US
dc.relation.isbasedon	10.1038/srep01762	en_US
dc.subject.mesh	Mesentery	en_US
dc.subject.mesh	Microcirculation	en_US
dc.subject.mesh	Leukocytes	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Rats	en_US
dc.subject.mesh	Rats, Wistar	en_US
dc.subject.mesh	Reperfusion Injury	en_US
dc.subject.mesh	Microscopy, Confocal	en_US
dc.subject.mesh	Male	en_US
dc.title	Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy	en_US
dc.type	Journal Article
utslib.citation.volume	3	en_US
utslib.for	1007 Nanotechnology	en_US
utslib.for	029901 Biological Physics	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Mathematical and Physical Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	open_access
pubs.publication-status	Published	en_US
pubs.volume	3	en_US

Abstract:

Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

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http://hdl.handle.net/10453/37059