Understanding Cisplatin Resistance Using Cellular Models

Publisher:
Taylor & Francis Inc
Publication Type:
Journal Article
Citation:
IUBMB Life, 2007, 59 (11), pp. 696 - 699
Issue Date:
2007-01
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Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts. A series of resis
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