Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorum

Mohamad, KY; Rekiki, A; Myers, G; Bavoil, PM; Rodolakis, A

Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorum

Mohamad, KY Rekiki, A Myers, G

Bavoil, PM Rodolakis, A

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Publication Type:: Journal Article
Citation:: Veterinary Research, 2008, 39 (6)
Issue Date:: 2008-11-01

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Field	Value	Language
dc.contributor.author	Mohamad, KY	en_US
dc.contributor.author	Rekiki, A	en_US
dc.contributor.author	Myers, G https://orcid.org/0000-0002-4756-4810	en_US
dc.contributor.author	Bavoil, PM	en_US
dc.contributor.author	Rodolakis, A	en_US
dc.date.issued	2008-11-01	en_US
dc.identifier.citation	Veterinary Research, 2008, 39 (6)	en_US
dc.identifier.issn	0928-4249	en_US
dc.identifier.uri	http://hdl.handle.net/10453/39748
dc.description.abstract	Bacteria of the family Chlamydiaceae are obligate intracellular pathogens of human and animals. Chlamydophila pecorum is associated with different pathological conditions in ruminants, swine and koala. To characterize a coding tandem repeat (CTR) identified at the 3' end of incA gene of C. pecorum, 51 strains of different chlamydial species were examined. The CTR were observed in 18 of 18 tested C. pecorum isolates including symptomatic and asymptomatic animals from diverse geographical origins. The CTR were also found in two strains of C. abortus respectively isolated from faeces from a healthy ewe and from a goat belonging to asymptomatic herds, but were absent in C. abortus strains isolated from clinical disease specimens, and in tested strains of C. psittaci, C. caviae, C. felis and C. trachomatis. The number of CTR repeats is variable and encode several motifs that are rich in alanine and proline. The CTR-derived variable structure of incA, which encode the Chlamydiaceae-specific type III secreted inclusion membrane protein, IncA, may be involved in the adaptation of C. pecorum to its environment by allowing it to persist in the host cell. © 2008 INRA EDP Sciences.	en_US
dc.relation.ispartof	Veterinary Research	en_US
dc.relation.isbasedon	10.1051/vetres:2008032	en_US
dc.subject.classification	Veterinary Sciences	en_US
dc.title	Identification and characterisation of coding tandem repeat variants in incA gene of Chlamydophila pecorum	en_US
dc.type	Journal Article
utslib.citation.volume	6	en_US
utslib.citation.volume	39	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	0707 Veterinary Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	open_access
pubs.issue	6	en_US
pubs.publication-status	Published	en_US
pubs.volume	39	en_US

Abstract:

Bacteria of the family Chlamydiaceae are obligate intracellular pathogens of human and animals. Chlamydophila pecorum is associated with different pathological conditions in ruminants, swine and koala. To characterize a coding tandem repeat (CTR) identified at the 3' end of incA gene of C. pecorum, 51 strains of different chlamydial species were examined. The CTR were observed in 18 of 18 tested C. pecorum isolates including symptomatic and asymptomatic animals from diverse geographical origins. The CTR were also found in two strains of C. abortus respectively isolated from faeces from a healthy ewe and from a goat belonging to asymptomatic herds, but were absent in C. abortus strains isolated from clinical disease specimens, and in tested strains of C. psittaci, C. caviae, C. felis and C. trachomatis. The number of CTR repeats is variable and encode several motifs that are rich in alanine and proline. The CTR-derived variable structure of incA, which encode the Chlamydiaceae-specific type III secreted inclusion membrane protein, IncA, may be involved in the adaptation of C. pecorum to its environment by allowing it to persist in the host cell. © 2008 INRA EDP Sciences.

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http://hdl.handle.net/10453/39748