The lung communication network

Losa, D; Chanson, M

The lung communication network

Losa, D

Chanson, M

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Publication Type:: Journal Article
Citation:: Cellular and Molecular Life Sciences, 2015, 72 (15), pp. 2793 - 2808
Issue Date:: 2015-08-24

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Field	Value	Language
dc.contributor.author	Losa, D https://orcid.org/0000-0001-5219-3244	en_US
dc.contributor.author	Chanson, M	en_US
dc.date.available	2015-06-11	en_US
dc.date.issued	2015-08-24	en_US
dc.identifier.citation	Cellular and Molecular Life Sciences, 2015, 72 (15), pp. 2793 - 2808	en_US
dc.identifier.issn	1420-682X	en_US
dc.identifier.uri	http://hdl.handle.net/10453/41433
dc.description.abstract	© 2015 Springer Basel. The different types of cells in the lung, from the conducting airway epithelium to the alveolar epithelium and the pulmonary vasculature, are interconnected by gap junctions. The specific profile of gap junction proteins, the connexins, expressed in these different cell types forms compartments of intercellular communication that can be further shaped by the release of extracellular nucleotides via pannexin1 channels. In this review, we focus on the physiology of connexins and pannexins and describe how this lung communication network modulates lung function and host defenses in conductive and respiratory airways.	en_US
dc.relation.ispartof	Cellular and Molecular Life Sciences	en_US
dc.relation.isbasedon	10.1007/s00018-015-1960-9	en_US
dc.subject.classification	Biochemistry & Molecular Biology	en_US
dc.subject.mesh	Lung	en_US
dc.subject.mesh	Respiratory Mucosa	en_US
dc.subject.mesh	Gap Junctions	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Humans	en_US
dc.subject.mesh	Connexins	en_US
dc.subject.mesh	Cell Communication	en_US
dc.subject.mesh	Signal Transduction	en_US
dc.title	The lung communication network	en_US
dc.type	Journal Article
utslib.citation.volume	15	en_US
utslib.citation.volume	72	en_US
utslib.for	0601 Biochemistry and Cell Biology	en_US
utslib.for	1103 Clinical Sciences	en_US
utslib.for	0606 Physiology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - ithree - Institute of Infection, Immunity and Innovation
utslib.copyright.status	open_access
pubs.issue	15	en_US
pubs.publication-status	Published	en_US
pubs.volume	72	en_US

Abstract:

© 2015 Springer Basel. The different types of cells in the lung, from the conducting airway epithelium to the alveolar epithelium and the pulmonary vasculature, are interconnected by gap junctions. The specific profile of gap junction proteins, the connexins, expressed in these different cell types forms compartments of intercellular communication that can be further shaped by the release of extracellular nucleotides via pannexin1 channels. In this review, we focus on the physiology of connexins and pannexins and describe how this lung communication network modulates lung function and host defenses in conductive and respiratory airways.

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http://hdl.handle.net/10453/41433