MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood.

Cohen, A; Combes, V; Grau, GE

MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood.

Cohen, A Combes, V

Grau, GE

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Publication Type:: Journal Article
Citation:: J Neuroinfect Dis, 2015, 6 (1)
Issue Date:: 2015-03

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Field	Value	Language
dc.contributor.author	Cohen, A	en_US
dc.contributor.author	Combes, V https://orcid.org/0000-0003-2178-3596	en_US
dc.contributor.author	Grau, GE	en_US
dc.date.issued	2015-03	en_US
dc.identifier.citation	J Neuroinfect Dis, 2015, 6 (1)	en_US
dc.identifier.issn	2314-7334	en_US
dc.identifier.uri	http://hdl.handle.net/10453/41443
dc.description.abstract	Malaria is a mosquito-borne infectious disease caused by parasitic protozoa of the genus Plasmodium. It remains a major problem affecting humans today, especially children. However, the pathogenesis of malaria, especially severe malaria, remains incompletely understood, hindering our ability to treat this disease. Of recent interest is the role that small, non-coding RNAs play in the progression, pathogenesis of, and resistance to, malaria. Independent studies have now revealed the presence of microRNA (miRNA) in the malaria parasite, vector, and host, though these studies are relatively few. Here, we review these studies, focusing on the roles specific miRNA have in the disease, and how they may be harnessed for therapeutic purposes.	en_US
dc.language	eng	en_US
dc.relation.ispartof	J Neuroinfect Dis	en_US
dc.title	MicroRNAs and Malaria - A Dynamic Interaction Still Incompletely Understood.	en_US
dc.type	Journal Article
utslib.citation.volume	1	en_US
utslib.citation.volume	6	en_US
utslib.location.activity	Egypt	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	1107 Immunology	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	open_access
pubs.issue	1	en_US
pubs.publication-status	Published	en_US
pubs.volume	6	en_US

Abstract:

Malaria is a mosquito-borne infectious disease caused by parasitic protozoa of the genus Plasmodium. It remains a major problem affecting humans today, especially children. However, the pathogenesis of malaria, especially severe malaria, remains incompletely understood, hindering our ability to treat this disease. Of recent interest is the role that small, non-coding RNAs play in the progression, pathogenesis of, and resistance to, malaria. Independent studies have now revealed the presence of microRNA (miRNA) in the malaria parasite, vector, and host, though these studies are relatively few. Here, we review these studies, focusing on the roles specific miRNA have in the disease, and how they may be harnessed for therapeutic purposes.

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http://hdl.handle.net/10453/41443