Spider neurotoxins targeting voltage-gated sodium channels

Taylor & Francis Inc
Publication Type:
Journal Article
Toxin Reviews, 2005, 24 (38810), pp. 315 - 345
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The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides, and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate sodium channel gating and/or kinetics. A nu
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