CSTX-1, A Toxin From The Venom Of The Hunting Spider Cupiennius Salei, Is A Selective Blocker Of L-type Calcium Channels In Mammalian Neurons

Pergamon-elsevier Science Ltd
Publication Type:
Journal Article
Neuropharmacology, 2007, 52 (8), pp. 1650 - 1662
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The inhibitor cystine-knot motif identified in the structure of CSTX-1 from Cupiennius salei venom suggests that this toxin may act as a blocker of ion channels. Whole-cell patch-clamp experiments performed on cockroach neurons revealed that CSTX-1 produ
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