Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers

Publisher:
Pergamon-Elsevier Science Ltd
Publication Type:
Journal Article
Citation:
Neuropharmacology, 2005, 49 (5), pp. 669 - 686
Issue Date:
2005-01
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The basis for the neuroprotectant effect of D-mannitol in reducing the sensory neurological disturbances seen in ciguatera poisoning, is unclear. Pacific ciguatoxin-1 (P-CTX-1), at a concentration 10 nM, caused a statistically significant swelling of rat
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