Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography

Jones, AC; Sheppard, AP; Sok, RM; Arns, CH; Limaye, A; Averdunk, H; Brandwood, A; Sakellariou, A; Senden, TJ; Milthorpe, BK; Knackstedt, MA

Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography

Jones, AC Sheppard, AP Sok, RM Arns, CH Limaye, A Averdunk, H Brandwood, A Sakellariou, A Senden, TJ Milthorpe, BK

Knackstedt, MA

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Publication Type:: Journal Article
Citation:: Physica A: Statistical Mechanics and its Applications, 2004, 339 (1-2), pp. 125 - 130
Issue Date:: 2004-08-01

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Field	Value	Language
dc.contributor.author	Jones, AC	en_US
dc.contributor.author	Sheppard, AP	en_US
dc.contributor.author	Sok, RM	en_US
dc.contributor.author	Arns, CH	en_US
dc.contributor.author	Limaye, A	en_US
dc.contributor.author	Averdunk, H	en_US
dc.contributor.author	Brandwood, A	en_US
dc.contributor.author	Sakellariou, A	en_US
dc.contributor.author	Senden, TJ	en_US
dc.contributor.author	Milthorpe, BK https://orcid.org/0000-0002-0867-9586	en_US
dc.contributor.author	Knackstedt, MA	en_US
dc.date.issued	2004-08-01	en_US
dc.identifier.citation	Physica A: Statistical Mechanics and its Applications, 2004, 339 (1-2), pp. 125 - 130	en_US
dc.identifier.issn	0378-4371	en_US
dc.identifier.uri	http://hdl.handle.net/10453/8288
dc.description.abstract	We demonstrate the capability of X-ray micro-computed tomography to image the micro-structure of human cortical bone. At 5 μm voxel size we observe the complex morphology of the Haversian network in three dimensions. The local thickness of Haversian canals is measured using a maximal sphere algorithm and found to have a bimodal signature and a mean radius of 19.2 μm. The intra-cortical porosity due to Haversian canals is measured as 3.0%. Both results are in agreement with traditional histomorphometric measurements. We show that at higher resolutions one can resolve the spatial distribution of lacunae in cortical bone. © 2004 Elsevier B.V. All rights reserved.	en_US
dc.relation.ispartof	Physica A: Statistical Mechanics and its Applications	en_US
dc.relation.isbasedon	10.1016/j.physa.2004.03.046	en_US
dc.subject.classification	Fluids & Plasmas	en_US
dc.title	Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography	en_US
dc.type	Journal Article
utslib.citation.volume	1-2	en_US
utslib.citation.volume	339	en_US
utslib.for	0105 Mathematical Physics	en_US
utslib.for	0102 Applied Mathematics	en_US
utslib.for	0206 Quantum Physics	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
utslib.copyright.status	closed_access
pubs.issue	1-2	en_US
pubs.publication-status	Published	en_US
pubs.volume	339	en_US

Abstract:

We demonstrate the capability of X-ray micro-computed tomography to image the micro-structure of human cortical bone. At 5 μm voxel size we observe the complex morphology of the Haversian network in three dimensions. The local thickness of Haversian canals is measured using a maximal sphere algorithm and found to have a bimodal signature and a mean radius of 19.2 μm. The intra-cortical porosity due to Haversian canals is measured as 3.0%. Both results are in agreement with traditional histomorphometric measurements. We show that at higher resolutions one can resolve the spatial distribution of lacunae in cortical bone. © 2004 Elsevier B.V. All rights reserved.

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http://hdl.handle.net/10453/8288