Three-dimensional analysis of cortical bone structure using X-ray micro-computed tomography

Elsevier Inc
Publication Type:
Journal Article
Physica A: Statistical Mechanics and its Applications, 2004, 339 (1-2), pp. 125 - 130
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We demonstrate the capability of X-ray micro-computed tomography to image the micro-structure of human cortical bone. At 5 ?m voxel size we observe the complex morphology of the Haversian network in three dimensions. The local thickness of Haversian canals is measured using a maximal sphere algorithm and found to have a bimodal signature and a mean radius of 19.2 ?m. The intra-cortical porosity due to Haversian canals is measured as 3.0%. Both results are in agreement with traditional histomorphometric measurements. We show that at higher resolutions one can resolve the spatial distribution of lacunae in cortical bone.
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