Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues

Publication Type:
Journal Article
Tetrahedron, 2005, 61 (7), pp. 1803 - 1812
Issue Date:
Filename Description Size
Thumbnail2008005064OK.pdf396.86 kB
Adobe PDF
Full metadata record
The conformationally restricted glutamate analogues, 4-aryl-1-amino-2- cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of 12a and 12b indicates that both compounds are modest antagonists at mGluR2. © 2004 Elsevier Ltd. All rights reserved.
Please use this identifier to cite or link to this item: