Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica

Amer Soc Biochemistry Molecular Biology Inc
Publication Type:
Journal Article
Journal Of Biological Chemistry, 2008, 283 (15), pp. 9896 - 9908
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The helminth parasite Fasciola hepatica secretes cysteine proteases to facilitate tissue invasion, migration, and development within the mammalian host. The major proteases cathepsin L1 (FheCL1) and cathepsin L2 (FheCL2) were recombinantly produced and b
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