Changes in the activity of osteoblast like cells with sol-gel derived hydroxyapatite and zirconia nanocoatings

Lewis, K; Valenzuela, SM; Ben-Nissan, B

Changes in the activity of osteoblast like cells with sol-gel derived hydroxyapatite and zirconia nanocoatings

Lewis, K Valenzuela, SM

Ben-Nissan, B

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Publication Type:: Journal Article
Citation:: Key Engineering Materials, 2008, 361-363 I pp. 633 - 636
Issue Date:: 2008-01-28

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Field	Value	Language
dc.contributor.author	Lewis, K	en_US
dc.contributor.author	Valenzuela, SM https://orcid.org/0000-0001-5934-6047	en_US
dc.contributor.author	Ben-Nissan, B	en_US
dc.date.issued	2008-01-28	en_US
dc.identifier.citation	Key Engineering Materials, 2008, 361-363 I pp. 633 - 636	en_US
dc.identifier.issn	1013-9826	en_US
dc.identifier.uri	http://hdl.handle.net/10453/9391
dc.description.abstract	When producing implant materials, achievement of optimal bioactivity and biocompatibility are essential. Nanocoatings can provide an efficient cost effective way to alter the interactions of the implant material with its destined "host" environment. Nanocoatings of sol-gel derived carbonated hydroxyapatite (HAp) and zirconia were produced in this study. The surfaces were characterised by Fourier transform infrared spectroscopy (FTIR) and light microscopy. Cell adhesion, proliferation and viability, as well as expression of alkaline phosphatase (ALP is an indicator of bone formation) were assessed as indicators of biocompatibility. Our results have shown that sol-gel derived nano crystalline HAp acts as an ideal surface for implant coatings.	en_US
dc.relation.ispartof	Key Engineering Materials	en_US
dc.subject.classification	Materials	en_US
dc.title	Changes in the activity of osteoblast like cells with sol-gel derived hydroxyapatite and zirconia nanocoatings	en_US
dc.type	Journal Article
utslib.citation.volume	361-363 I	en_US
utslib.for	0915 Interdisciplinary Engineering	en_US
utslib.for	09 Engineering	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
pubs.organisational-group	/University of Technology Sydney/Strength - CHT - Health Technologies
pubs.organisational-group	/University of Technology Sydney/Strength - IBMD - Initiative for Biomedical Devices
utslib.copyright.status	open_access
pubs.publication-status	Published	en_US
pubs.volume	361-363 I	en_US

Abstract:

When producing implant materials, achievement of optimal bioactivity and biocompatibility are essential. Nanocoatings can provide an efficient cost effective way to alter the interactions of the implant material with its destined "host" environment. Nanocoatings of sol-gel derived carbonated hydroxyapatite (HAp) and zirconia were produced in this study. The surfaces were characterised by Fourier transform infrared spectroscopy (FTIR) and light microscopy. Cell adhesion, proliferation and viability, as well as expression of alkaline phosphatase (ALP is an indicator of bone formation) were assessed as indicators of biocompatibility. Our results have shown that sol-gel derived nano crystalline HAp acts as an ideal surface for implant coatings.

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http://hdl.handle.net/10453/9391