Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini

Public Library Science
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Journal Article
Plos Neglected Tropical Diseases, 2009, 3 (3), pp. 1 - 15
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The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.
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