Cardiac Transgenesis With The Tetracycline Transactivator Changes Myocardial Function And Gene Expression

Amer Physiological Soc
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Journal Article
Physiological Genomics, 2005, 22 (1), pp. 118 - 126
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The cardiac-specific tetracycline-regulated gene expression system (tet-system) is a powerful tool using double-transgenic mice. The cardiac alpha-myosin heavy chain promoter (alpha MHC) drives lifetime expression of a tetracycline-inhibited transcriptio
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