Isolation of Toxoplasma gondii from the brain of a dog in Australia and its biological and molecular characterization

Al-Qassab, S; Reichel, MP; Su, C; Jenkins, D; Hall, C; Windsor, PA; Dubey, JP; Ellis, J

Isolation of Toxoplasma gondii from the brain of a dog in Australia and its biological and molecular characterization

Al-Qassab, S Reichel, MP

Su, C Jenkins, D Hall, C Windsor, PA Dubey, JP Ellis, J

Permalink

Publication Type:: Journal Article
Citation:: Veterinary Parasitology, 2009, 164 (2-4), pp. 335 - 339
Issue Date:: 2009-10-14

Open Access

Copyright Clearance Process

Recently Added
In Progress
Open Access

This item is open access.

Adobe PDF

Download full textAdobe PDF (389.57 kB)

View on publisher's site

View statistics

Full metadata record

Field	Value	Language
dc.contributor.author	Al-Qassab, S	en_US
dc.contributor.author	Reichel, MP https://orcid.org/0000-0002-9792-8336	en_US
dc.contributor.author	Su, C	en_US
dc.contributor.author	Jenkins, D	en_US
dc.contributor.author	Hall, C	en_US
dc.contributor.author	Windsor, PA	en_US
dc.contributor.author	Dubey, JP	en_US
dc.contributor.author	Ellis, J https://orcid.org/0000-0001-7328-4831	en_US
dc.date.available	2009-05-06	en_US
dc.date.issued	2009-10-14	en_US
dc.identifier.citation	Veterinary Parasitology, 2009, 164 (2-4), pp. 335 - 339	en_US
dc.identifier.issn	0304-4017	en_US
dc.identifier.uri	http://hdl.handle.net/10453/9712
dc.description.abstract	Toxoplasma gondii was isolated from the brain of a young dog for the first time in Australia. The identity of the parasite was confirmed by PCR, Western blotting, electron microscopy and cat bioassay. Genotyping of the isolate (TgDgAu1) was determined by PCR-RFLP markers that showed it to be a Type II strain. Western blotting demonstrated the presence of IgM antibodies to T. gondii suggesting the bitch was probably infected during pregnancy and the T. gondii was transmitted to the pups congenitally. We believe this represents the first description of a natural case of congenital transmission of T. gondii in the dog. © 2009 Elsevier B.V.	en_US
dc.relation.ispartof	Veterinary Parasitology	en_US
dc.relation.isbasedon	10.1016/j.vetpar.2009.05.019	en_US
dc.subject.classification	Mycology & Parasitology	en_US
dc.subject.mesh	Animals	en_US
dc.subject.mesh	Dogs	en_US
dc.subject.mesh	Cats	en_US
dc.subject.mesh	Mice	en_US
dc.subject.mesh	Rats	en_US
dc.subject.mesh	Rats, Wistar	en_US
dc.subject.mesh	Toxoplasma	en_US
dc.subject.mesh	Toxoplasmosis, Animal	en_US
dc.subject.mesh	Cat Diseases	en_US
dc.subject.mesh	Dog Diseases	en_US
dc.subject.mesh	Antibodies, Protozoan	en_US
dc.subject.mesh	Pregnancy	en_US
dc.subject.mesh	Genotype	en_US
dc.subject.mesh	Australia	en_US
dc.subject.mesh	Female	en_US
dc.title	Isolation of Toxoplasma gondii from the brain of a dog in Australia and its biological and molecular characterization	en_US
dc.type	Journal Article
utslib.citation.volume	2-4	en_US
utslib.citation.volume	164	en_US
utslib.for	0605 Microbiology	en_US
utslib.for	0704 Fisheries Sciences	en_US
utslib.for	0707 Veterinary Sciences	en_US
pubs.embargo.period	Not known	en_US
pubs.organisational-group	/University of Technology Sydney
pubs.organisational-group	/University of Technology Sydney/Faculty of Science
pubs.organisational-group	/University of Technology Sydney/Faculty of Science/School of Life Sciences
utslib.copyright.status	open_access
pubs.issue	2-4	en_US
pubs.publication-status	Published	en_US
pubs.volume	164	en_US

Abstract:

Toxoplasma gondii was isolated from the brain of a young dog for the first time in Australia. The identity of the parasite was confirmed by PCR, Western blotting, electron microscopy and cat bioassay. Genotyping of the isolate (TgDgAu1) was determined by PCR-RFLP markers that showed it to be a Type II strain. Western blotting demonstrated the presence of IgM antibodies to T. gondii suggesting the bitch was probably infected during pregnancy and the T. gondii was transmitted to the pups congenitally. We believe this represents the first description of a natural case of congenital transmission of T. gondii in the dog. © 2009 Elsevier B.V.

Please use this identifier to cite or link to this item:

http://hdl.handle.net/10453/9712